There are very few "constants" between KLRs, especially when you start rejetting. I installed a new jet kit from Dynojet (Moose Racing) and started with their basic instructions then tuned from there. At idle, after warming the engine, I ran the screw lean and rich until I found the drop in RPM both directions and settled in the middle (about 1.75 turns in my case). Then I checked the needle setting by installing a clean plug, running it and checking the plug. I also checked for engine performance on acceleration, missing at cruise usually indicates lean, bogging indicates rich. Then I checked the main jet almost the same way (but faster). When everything was done I still fussed with the gas cap vent (why it would start sticking is anyones guess, but a shot of silicone spray fixed it).
Did you drill the slide?
"My KLR belongs to God, when he wants it clean he washes it."