I've done it several times, and still don't much care for it. If you are on public roads, the cars drive along packing everything all down and making it effectively into ice. My biggest fear isn't crashing, (because I know that is going to happen more often in the snow) but getting run over by somebody that doesn't see me, or can't stop.
I run a full knobby, last winter was the T63, this winter has mostly been the MT21. If I were smart, I'd stop cheaping out, and order a nice stud gun and stud up the tires. In the mean time, I know and understand my limits, I'll push them, but I always have an agreement that if things get far outside my comfort zone, I will park the bike and walk.
Side note: With a full knob, ditches and medians have far more available traction than packed snow on a paved road.
As Kenny Roger's said, "you got to know when to hold 'em, know when to fold 'em, know when to walk away, and know when to run!"