I did a mileage run yesterday. Almost 100 miles out and back on the same road. I maintained as close to 65 MPH as I could. The road was fairly smooth interstate, fairly flat with some mild grades, wind was light, temp 48 degrees. I checked chain adjustment and lubed it with chain wax before starting. I recently rebuilt the top end with an EM 692 kit and refreshed head. I weigh about 230lbs in shorts, I was wearing all the gear since it was 48 degrees, the bike has panniers on it with a few pounds in each side. Sprockets are stock 15/43. It has the stock jets and needle in the carb.
I filled the tank to the bottom of the fuel filler pipe at a gas station along I-5 in Washington, rode out 49.3 miles, turned around at an interchange and rode back to the same gas station, filled it up at the same gas pump with the bike in the exact same location, and filled it until the fuel just touched the bottom of the filler pipe. 45.3 MPG.
I also measured my mileage over a 96 mile run last week and got 51.1 MPG, but I was mostly on secondary roads going between 50-60MPH, with about 25 miles of interstate at 65. Apparently speed and/or RPM makes a big difference in fuel consumption.